Developing new therapies and getting them to patients is long and difficult. During public health emergencies, such as the Covid-19 Pandemic, science must move faster than ever. That is where translational science comes in. Translational science is focused on streamlining the process of moving (“translating”) lab findings into medical practice and treatments to improve health and well-being.
NCATS is supporting research activities spanning the translational science spectrum to address the novel coronavirus 2019 (SARS-CoV-2) and the disease it causes (COVID-19). To accelerate translational research, NCATS has developed research tools, technologies, expertise and collaborative networks that can quickly pivot to address urgent public health issues.
- The mission of the Irving Institute for Clinical and Translational Research is to advance discoveries, knowledge, and innovation to improve human health across the lifespan for diverse populations in upper Manhattan and around the world. By mobilizing and connecting Columbia University’s researchers, we aim to create a seamless integration of community and academic partnerships. Our commitment to train a multi-faceted workforce, provide vital resources to researchers, and improve the efficiency of research processes, promotes the collaborative team science framework needed to translate research discoveries into effective interventions that address current and future health concerns.
We provide over 70 different services and programs focused on education and training, seed funding, bioinformatics, biostatistics, clinical research, lifespan research and special populations, regulatory knowledge and bioethics, an off-site community facility and health informatics websites.
- January 13, 2022At this point in the pandemic, you or someone you know has probably received at least one COVID-19 test. But do you know which kind of test you got and the strengths and weaknesses of these different tests?
- January 12, 2022University of Florida faculty are leading a multistate team to boost COVID-19 and influenza vaccination rates in parts of the country where health care skepticism is common and vaccination rates are low. With the emergence of the highly contagious omicron COVID-19 variant, experts say it is more important than ever to provide people with information and access to protective vaccines. The Our
- January 11, 2022
Shots trigger exceptional antibody response by activating key helper immune cells
- January 05, 2022A crucial effort by UC Davis Health to detect COVID-19 among farmworkers and other vulnerable populations has resulted in more than 17,000 coronavirus rapid tests given to residents of four Central California counties. Underway since early February, the effort known as ÓRALE offers free COVID-19 screening primarily to Latinos with a focus on agricultural essential workers at locations and hours
- December 01, 2021Organ transplant recipients and people living with HIV are more likely to experience adverse effects after contracting COVID-19. And kidney and heart transplant recipients are at highest risk. Those are just some of the conclusions coming from an international team of researchers that includes Virginia Commonwealth University data scientists. Amy Olex, M.S., and Evan French of the Wright Center
- November 23, 2021“Without a doubt, the support from the Georgia CTSA changed the trajectory of my career. It connected me to mentors, protected time and matched me with clinical research which is so important to me,” says Colleen S. Kraft, MD, MSc. Known as one of Emory’s leading infectious disease experts, Colleen S. Kraft, MD, MSc, is no stranger to today’s media outlets and the medical community for her role as
- November 22, 2021The University of Pennsylvania will be conducting a mixed methods study, funded by NCATS through a bioethics supplement to the University of Pennsylvania’s CTSA, to examine institutional approaches to prioritizing COVID-19 trials. The goal of this study is to understand relevant processes and criteria applied during the pandemic, as well as perspectives on potentially extending these approaches to
- November 19, 2021You wake up one morning with a fever and a cough. Where can you get a rapid, accurate COVID-19 test? The answer has plagued many people in the U.S., where the FDA has been slow to approve at-home, rapid tests, many of which suffer from high false-negative rates. And the more-accurate polymerase chain reaction (PCR) COVID-19 test preferred by clinics and health care providers takes many hours to
- November 17, 2021
Even now — nearly two years after the pandemic began — the totality of COVID-19’s ever-evolving health and economic consequences remain unclear. The pandemic’s ripple effect has impacted a multitude of interconnected variables leading to a staggering array of outcomes. A team of Ohio State researchers in the Department of Economics was recently awarded a five-year, $2.3 million grant from the
- November 13, 2021Former KL2 scholars and current Georgia CTSA Research Education Program members, Dr. Igho Ofotokun and Dr. Rachel Patzer, along with Georgia CTSA Clinical Research Centers Co-Director, Dr. Priscilla Pemu, received a nearly $20M NIH grant as principal investigators of the Atlanta hub for RECOVER, a nationwide effort to study Long COVID effects. Georgia CTSA Community Engagement Director, Dr. Tabia
- Pennsylvania State Univ Hershey Med Ctr
Objectives: The goal of this study was to examine the attitudes of PA rural residents toward data sharing in the setting of the COVID-19 pandemic and ultimately better understand rural residents’ willingness to provide personal information to public health staff investigating COVID-19 cases, as well as their concerns. Methods: 4000 surveys were mailed to rural residents identified from the
- November 05, 2021
The Weill Cornell Clinical and Translational Science Center (CTSC) with partner Hunter College School of Nursing, initiated a community vaccination program in February 2020 for underserved communities in New York City. Alarmed by the growing disparities in vaccination of minorities, Reverend Patrick O’Connor of First Presbyterian Church in Jamaica Queens, reached out to Julianne Imperato-McGinley
- University Of Colorado DenverBackground: The University of Colorado Anschutz Medical Campus (CU-Anschutz) is a complex research environment comprised of three hospitals and multiple University research entities, including Colorado Clinical and Translational Sciences Institute (CCTSI; CTSA. CU-AMC has over $600M in research grants and over 4,000 clinical research protocols and trials. COVID-19 suspended almost all clinical
- University Of Southern California
This poster outlines and explains the purpose, strategies, and results associated with the VaccinateLA initiative, an interdisciplinary, multimedia health campaign designed to improve vaccination rates in high-disparity communities around Los Angeles, California.
- Washington University
Introduction: The STOP COVID Trials were innovative fully-remote randomized controlled trials of fluvoxamine (a sigma1 receptor agonist with anti-inflammatory properties) vs placebo for treatment of outpatients with early COVID-19 who were self-isolating at home. Methods: The trials used eConsent and an electronic data capture system with integrated recruitment from the EPIC electronic health
- -Pennsylvania State Univ Hershey Med Ctr
TriNetX is a powerful tool for real-world research, putting millions of data points at your fingertips in minutes. But with great power comes great potential pitfalls. Spend time with two experienced members of the TriNetX team and a recent author from Penn State College of Medicine to learn how to maximize your chances for successful publication at every step along the journey, from query design
- November 03, 2021
Laura Mussulman, MA, MPH, has been named the Director of Clinical and Translational Science Unit (CTSU) Fairway at the University of Kansas Medical Center, effective Monday, November 8, 2021. Mussulman will direct all CTSU Fairway operations and supervise the CTSU nursing and research staff. She will also partner with the other Frontiers CTSUs at KUMC Rainbow, KU Wichita, and Children's Mercy
- October 28, 2021
The Washington University Pediatric and Adolescent Research Consortium (WU PAARC), a practice-based research network of community pediatric healthcare providers, has been an integral part of the ICTS since the inception of the CTSA program at Washington University in 2007. As a core of the ICTS and a part of the Integrating Special Populations function, WU PAARC continually fosters partnerships
- October 08, 2021Sense of smell or taste returns within six months for 4 out of every 5 COVID-19 survivors who have lost these senses, and those under 40 are more likely to recover these senses than older adults, an ongoing Virginia Commonwealth University study found. Among 798 respondents to the ongoing COVID-19 smell and taste loss survey who had tested positive for COVID-19 and reported a loss of smell or
- October 06, 2021Inflammasomes were discovered in 2002, and almost 20 years later, the number of diseases for which the molecule has treatment implications continues to expand. “It’s amazing how the implications are growing to so many different diseases, whether it’s gout, heart disease, cancer or addiction,” said P. Srirama Rao, Ph.D., VCU’s vice president for research and innovation. “Even more recently, in the
- October 04, 2021
Efforts to educate and promote the COVID-19 vaccine continue and rates have gone up, but there are still communities struggling to get vaccinated. Whether low vaccination rates are due to misinformation or lack of accessibility, it has become apparent that not all communities in the U.S. are suffering in the same ways from the COVID-19 pandemic. Several groups in California have made it their
- September 30, 2021
As the country rides a new wave of the COVID-19 pandemic, it faces a riptide that’s threatening its course. The delta variant, the now-predominant strain of coronavirus, prompted President Joe Biden’s call for booster shots for all vaccinated adults on Aug. 18 and underscored discussions at a research summit that ran parallel to the president’s nationwide address. “This is, of course, something
- University Of Southern California
COVID-19 has thrown a wrench into research conduct, forcing hospitals and universities to transfer their research plans, data collection procedures, survey dissemination processes, and participant engagement methods quickly and nimbly to online venues. In addition, the state of research operations has changed dramatically due to the pandemic. This guide provides key considerations for ensuring
- September 29, 2021
In the early days of the pandemic, with commercial COVID tests in short supply, Rockefeller’s Robert B. Darnell developed an in-house assay to identify positive cases within the Rockefeller community. It turned out to be easier and safer to administer than the tests available at the time, and it has been used tens of thousands of times over the past nine months to identify and isolate infected
- September 23, 2021Sergio Aguilar-Gaxiola, program director of the UC Davis CTSC Community Engagement program, was invited to provide commentary on another team's publication. The article, published Sept. 15, focuses on farmworkers’ lack of access to health care during COVID-19.
- September 13, 2021
Washington University ICTS supported research shows that rapid saliva test screenings – aimed at early detection of the virus – contributed to exceedingly low transmission of the virus among students, teachers and staff in the six schools overseen by the Special School District of St. Louis County, the largest specialized education provider in Missouri.
- September 13, 2021
Nearly 90% of people taking immunosuppressants to treat autoimmune conditions produce an antibody response to COVID-19 vaccination, but the response is weaker than those generated by healthy people, according to a study by ICTS researchers at Washington University School of Medicine.
- September 09, 2021
LITTLE ROCK — A University of Arkansas for Medical Sciences (UAMS) research team has identified a potential cause of long-lasting symptoms experienced by COVID-19 patients, often referred to as long-haulers. The findings were published in the journal, The Public Library of Science ONE (PLOS ONE). At the heart of the team’s findings is an antibody that shows up weeks after an initial infection and
- August 27, 2021Virginia Commonwealth University is launching a study of the impact of COVID-19 on twins to try to determine why some people experience symptoms much longer than others. The Twin 360 project, which began this week, will help researchers understand the genetic and environmental factors for why some people experience lasting symptoms after contracting COVID-19. And the research will inform possible