Clinical Research
Columbia University
The mission of the Irving Institute for Clinical and Translational Research is to advance discoveries, knowledge, and innovation to improve human health across the lifespan for diverse populations in upper Manhattan and around the world. By mobilizing and connecting Columbia University’s researchers, we aim to create a seamless integration of community and academic partnerships. Our commitment to train a multi-faceted workforce, provide vital resources to researchers, and improve the efficiency of research processes, promotes the collaborative team science framework needed to translate research discoveries into effective interventions that address current and future health concerns.
We provide over 70 different services and programs focused on education and training, seed funding, bioinformatics, biostatistics, clinical research, lifespan research and special populations, regulatory knowledge and bioethics, an off-site community facility and health informatics websites.
March 10, 2023Clinical notes in medical records are rich sources of data about human health. But tapping them for medical research can be challenging because these data come from various sources—and they all look different. "There's no standardization in how data is organized and classified across medical records systems," says Sunyang Fu, Ph.D., a Mayo Clinic biomedical informatics researcher. Even the
University Of MichiganClinical and translational investigators need patient data, especially from electronic health record (EHR) systems, to conduct research, but optimal approaches are unknown. This talk explores an approach for supporting different types of investigators and study designs by matching investigators with informatics tools and services.
-Virginia Commonwealth UniversityEffective participant recruitment and retention are critical components of clinical research. However, challenges with participant accrual are common, often compromising the ability to carry out investigations as intended. Robust recruitment and retention plans can greatly enhance the likelihood of responding to the study question to advance science. There is a related need to ensure that the
February 28, 2023by Jarrod Dalton, PhD, Director, Center for Populations Research, Cleveland Clinic Lerner Research Institute This article is a Health Disparities Researcher Self Portrait authored by a CTSC-supported health disparities researcher. I’m Jarrod Dalton, PhD, and I design new approaches to examining the systems fueling health inequity. My experience is shaped through decade-long relationships with
February 28, 2023Case Comprehensive Cancer Center’s Director of Community Engagement, Kristina Austin, Shares Evolution of the Symposium and Potential for Impact This article is a CTSC Special Feature. The Case Comprehensive Cancer Center (CCCC) Cancer Disparities Symposium (the “Symposium”) will turn seven years old this year. The brainchild of Dr. Monica Webb Hooper, current Deputy Director of the National
February 09, 2023Mission: Health Equity Challenge Series - Challenge #3 Reinforces Importance of Doing Research With Community Organizations Many people have preconceived notions about research. From the people who are considering going into research careers to patients turned prospective research participants thinking about participating in research studies. Some benefit from being a part of research in academia
February 02, 2023Oregon Health & Science University (OHSU) is participating in one of the first studies that tries to intervene earlier in the treatment and prevention of Alzheimer’s disease. It’s an international clinical trial called the AHEAD study, funded by the National Institutes of Health and the pharmaceutical company Eisai. The AHEAD study is both a test of a single promising drug and an effort to uncover
January 19, 2023The Miami Clinical and Translational Science Institute (CTSI) mourns the passing of its Director and MPI Ralph L. Sacco, M.D., M.S., a highly respected and beloved member of the UHealth and University of Miami Miller School of Medicine community, on January 17, from a glioblastoma. Dr. Sacco’s outstanding achievements and contributions in research, teaching and mentorship, and patient care made a
January 17, 2023The Urgency to Design and Implement DEI Strategies Shouldn’t Wait for Legislation This article is a part of our CTSC Special Feature series. What does pending legislation say about DEI strategy? What do most of these introduced bills have in common? Where and when do I start? With diversity, equity, inclusion, and accessibility at the forefront of clinical and translational science priorities
January 12, 2023Dr.Clara Pelfrey, Director of Evaluation for the Clinical and Translational Science Collaborative honored with the Ohio Program Evaluators Group (OPEG) Evaluation Recognition Award 2022. Clara has only been an evaluator for 10 years, she has helped advance evaluation in many ways in the Clinical and Translational Science Award (CTSA) Consortium. Clara and her colleagues pioneered a process for
January 12, 2023Since joining Case Western Reserve University School of Medicine in March 2022, Gelise Thomas has made an immediate impact by creating programs and leading initiatives to help researchers understand their roles in helping to close the gaps in health disparities. Gelise directs strategic diversity, equity, inclusion and accessibility (DEIA), and health disparities efforts in the CTSC, working with
January 12, 2023The Clinical and Translational Science Collaborative (CTSC) released its 2023 READI Programming offerings last month. Inspired by insights gleaned from READI news articles, conversations and feedback from the Mission: Health Equity Challenge Series, we will offer three tracks for exploration throughout the year. The tracks are: READI Research Policy Impact; READI Special Populations Roundtable
January 12, 2023The mission of our CTSC hub is to catalyze clinical and translational research across the Greater Cleveland area and beyond. Toward this goal, we are pleased to offer a new research resource! Whether you are a new investigator or seasoned researcher, the CTSC can support your proposal development process in a number of ways: Grant Writing Consultation Letter of Support Request Grant Writing
December 16, 2022New ranking from the National Science Foundation is achieved ahead of the schedule set by the university. Bolstered in part by the intense drive to fight the COVID-19 pandemic, Virginia Commonwealth University now ranks among the top 50 public research universities in the United States for the first time.
-Stanford UniversityThis 10-session course introduces the basics of clinical research design, including: biostatistics, design of diagnostic and predictive test studies, required/desired elements of clinical trial protocols, the regulatory aspects of clinical research conduct and oversight, Good Clinical Practice (GCP), and ethical dimensions of clinical research. Open to faculty, fellows and staff within the CTSA. A
December 07, 2022You probably learned about cilia in high school biology class. The tiny hairlike structures line our nasal passages, ears and airways. Children born with primary ciliary dyskinesia (PCD), a rare inherited disease, have problems with the cilia that prevent them from moving mucus and inhaled particles and germs out of their airways, causing mucus to build up, leading to ear, sinus and lung
-University Of North Carolina Chapel HillThe Society for Education and the Advancement of Research in Connected Health (SEARCH) is hosting their annual virtual SEARCH 2022—National Telehealth Research Symposium November 16-18, 2022. The 3-day conference will feature 70 speakers showcasing connected health initiatives, strategies, and partnerships, a broad scope of up-to-date telehealth research initiatives across the spectrum of healthcare delivery, research-focused educational programming, and promotion of telehealth policy and equity.
November 03, 2022An Advocate at Heart, Actionability is a Cornerstone of Rose’s Research Program This article is a part of our Health Disparities Researcher Feature series. Dr. Johnie Rose didn’t grow up wanting to be a scientist. His interest in policy and quantitative analysis led him to study economics in college. Working in the health insurance industry before going to medical school and earning a PhD in
November 03, 2022Individual Bias and its Impact on the Prevalence of Scientific Bias This article is a part of the DEI Resource Highlight series. Bias is defined as “prejudice in favor of or against one thing, person, or group compared with another, usually considered to be unfair.” One thing is certain, we all have biases. What happens when we’re not aware of those biases and we allow them to influence how we
October 06, 2022The University Hospitals Williams T. Dahms, MD Clinical Research Unit is celebrating its 60th Anniversary of continuous federal funding and 60 years of being at the forefront of pioneering, life-saving discoveries. A New Clinical Research Unit: First opened on June 17th, 1962 in the Lakeside Building, Div. 55 South, with a grant of $3.3 million from the U.S. Department Health, Education and
October 06, 2022On August 18th and 19th, the CTSC hosted a Department of Defense (DOD) themed Biomedical Research Symposium in the Wolstein Research Building at Case Western Reserve University. Based on the growing interest in a range of DOD-supported science areas, the symposium was divided into multiple sessions, covering a range of topics, from infectious disease to medical products for warfighter needs to
-Boston University Medical CampusRe-examining Our Approach to Research: Translational Science Lessons from the Pandemic The COVID-19 pandemic laid bare the urgent need to employ research methodologies better suited to more effectively, efficiently and equitably move therapeutics, vaccines and other interventions from bench to bedside to community. Reflecting on lessons learned, this conference will focus on successes and
September 20, 2022Jennifer L. Vincenzo, Ph.D., MPH, PT, recently became the first University of Arkansas for Medical Sciences (UAMS) researcher to receive the national Paul B. Beeson Emerging Leaders Career Development Award in Aging, which comes with $1 million over five years. The award will support Vincenzo’s work implementing a falls prevention strategy as a standard of care for all older adults attending
September 19, 2022COMMUNITY STAKEHOLDERS SAY BETTER TREATMENT GUIDANCE COULD BE USEFUL FOR PATIENTS Penn State faculty are joining clinical researchers from across the country to study treatment approaches for acute rhinosinusitis, also called “sinusitis.” The condition is an inflammation of the nose and sinus passages most often caused by a viral or bacterial infection that affects one in seven U.S. adults each
-University Of MichiganThe Electronic Medical Record Search Engine (EMERSE) was installed at University Hospitals of Cleveland (UH) in 2021 by the Cleveland Institute for Computational Biology (CICB), a collaboration between Case Western Reserve University (CWRU) and UH. At present, EMERSE contains indexed medical notes from 2018 through present for over 1.7 million UH patients. This presentation will discuss the
September 06, 2022Nine UMass undergraduate students were recognized for their summer research internship work as part of an inaugural multi-campus collaboration. This internship program was developed to give students from the UMass Amherst School of Public Health & Health Sciences and the UMass Lowell Zuckerberg College of Health Sciences the experience in clinical research, and to provide insight into the rewards
August 09, 2022In a June 13, 2022, JAMA Viewpoint article, Georgia CTSA investigator Carlos del Rio, MD, and his co-authors concluded, “Control of this growing international outbreak will require careful coordination among public health officials, clinicians, and the community to disseminate information, obtain appropriate diagnostic testing, implement contact tracing, and ensure that affected individuals and
August 04, 2022CNBC: Grace McComsey, professor at the School of Medicine, discussed new research into “long COVID” in an effort to understand the mysterious condition. “You’ll be able to access a lot of data, lots of samples on patients that otherwise I can’t do from my own site. It will take me obviously a lot of time and a lot of resources that I don’t have,” McComsey said. Click here to continue reading this
August 02, 2022Lack of Inclusive Data and Low Trust Remain Barriers to Advancement of Health Equity On Thursday, June 16, 2022, the Clinical and Translational Science Collaborative (CTSC) hosted a REAL (Racial Equity and the Law) Talk webinar, titled Clinical Research Law and Policy, with the Cleveland Metropolitan Bar Association. Gelise Thomas, Assistant Director, Strategic DEI & Health Disparities with the