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The Integrating CTS into the CTSA Virtual Visiting Scholar Program Working Group is pleased to announce a Grand Rounds Lecture. Please join us on Thursday, March 23, 2023 at 12:00pm ET. Casey Straud, PsyD, ABPP, Assistant Professor, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at San Antonio, will present: Translational Research on Cannabidiol to
The NCATS-funded Evolve to Next-Gen ACT (ENACT) is a collaborative research platform that will enable investigators at CTSA hubs to conduct EHR research on any disease or condition from their desktop. Using de-identified data from EHRs for >142 million patients at 57 hubs, ENACT will also allow data scientists to develop and test EHR-based research tools. ENACT is the next iteration of the ACT
Background: Implementation science aims to improve adoption, implementation, and sustainment of evidence-based practices or programs. We aimed to develop an approach to teach implementation science principles to a wide range of learners and that could accommodate a variety of frameworks, philosophies, and contexts. Methods: The 7-step model, Getting To Implementation (GTI)-Teach, was adapted from
KL2 awardees from Clinical and Translational Science Centers (CTSA) present virtual lectures as part of the CTSA Visiting Scholar program. Alex Bokov, PhD from the University of Texas Health Science Center San Antonio is hosted by the University of Pittsburgh, will discuss his research on "Mining EHR Data for Improved Outcomes Prediction".
Vasculitis refers to a group of rare diseases that involve inflammation of blood vessels, which disrupts blood flow and often causes damage to the body’s organs. The cause of most forms of vasculitis remains unknown, and treatments involve the use of strong medications that can have serious side effects. The Vasculitis Clinical Research Consortium (VCRC) is an international, multicenter clinical
The Phenylalanine Families and Researchers Exploring Evidence (PHEFREE) Consortium studies the health, neurologic, cognitive, neuropsychiatric, patient-reported and quality-of-life outcomes in individuals with chronic elevations of the amino acid phenylalanine in blood (hyperphenylalaninemia). In the United States, elevated blood phenylalanine is typically detected at birth through newborn
Mitochondrial diseases affect approximately 1 in every 5,000 people. These diseases can cause muscle weakness, difficulty thinking, seizures, hearing and vision loss, digestive problems, learning disabilities, and organ failure. The North American Mitochondrial Disease Consortium (NAMDC) is a network of clinicians and researchers at 17 different clinical sites working to better understand
Congenital disorders of glycosylation (CDG) consist of more than 130 different inborn errors of metabolism at an estimated overall incidence of greater than 1 in 100,000. While these disorders were first genetically defined in the 1990s, there is no data available on their natural history, no comprehensive patient registry, no reliable screening tests for many types, and large gaps in clinical
CovEx system has been deployed online and demonstrated to several target users. The early results indicate that the success of the system to a considerable extent depends on the quality of key phrase extraction. Moreover, the nature of exploratory search calls for special extraction approaches. While we used a relatively powerful approach, it was trained to model gold standard annotation of
The Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) is a clinical trials network funded by the National Institute for Neurological Disorders and Stroke (NINDS), the National Heart Lung and Blood Institute (NHLBI) and the National Center for Advancing Translational Science (NCATS). The goal of the SIREN Network is to improve the outcomes of patients with neurologic, cardiac
Founded on mutual interest rather than geographic proximity, the Sharing Partnership for Innovative Research in Translation (SPIRiT) Consortium links six CTSAs together to jointly develop innovative resources to support effective translational research. Consortium goals include promoting a sharing infrastructure for research data, tools, resources, and bio-specimens; establishing a network of
The University of Pittsburgh Clinical and Translational Science Institute (CTSI) launched the optional Innovation Core in 2015 with three aims: 1) Develop advanced, experiential innovation training, networking and externship opportunities and support the academic career development for biomedical innovators; 2) Develop and disseminate new methods and processes that encourage and support innovative
The CTSA Collaborative Data and Safety Monitoring Board (DSMB) Workgroup identified a need to provide guidance, training and resources in DSMB practices for investigator-initiated research studies. To promote clinical and translational research, the CTSA Collaborative DSMB Workgroup, supported by NCATS, has produced an online DSMB Training Manual with a focus on investigator-initiated studies