N3C
- Image
Columbia University
The mission of the Irving Institute for Clinical and Translational Research is to advance discoveries, knowledge, and innovation to improve human health across the lifespan for diverse populations in upper Manhattan and around the world. By mobilizing and connecting Columbia University’s researchers, we aim to create a seamless integration of community and academic partnerships. Our commitment to train a multi-faceted workforce, provide vital resources to researchers, and improve the efficiency of research processes, promotes the collaborative team science framework needed to translate research discoveries into effective interventions that address current and future health concerns.
We provide over 70 different services and programs focused on education and training, seed funding, bioinformatics, biostatistics, clinical research, lifespan research and special populations, regulatory knowledge and bioethics, an off-site community facility and health informatics websites. 
December 01, 2021Organ transplant recipients and people living with HIV are more likely to experience adverse effects after contracting COVID-19. And kidney and heart transplant recipients are at highest risk. Those are just some of the conclusions coming from an international team of researchers that includes Virginia Commonwealth University data scientists. Amy Olex, M.S., and Evan French of the Wright CenterBackground and Aims In patients with chronic liver diseases (CLD) with or without cirrhosis, existing data on the risk of adverse outcomes with SARS-CoV-2 infection have been mixed or have limited generalizability.
- Journal of Clinical Oncology
PURPOSE
May 26, 2021If you missed the webinar on Weds May 13th presented by Kenneth Gersing, MD, Director of Informatics NCATS DCI entitled Studying COVID-19 Using Real-World Data: Lessons Learned and Steps Forward After One Year of the National COVID Cohort Collaborative (N3C), you can now access the recording. Topics include: • Lessons learned after one year of studying COVID-19 using real-world data • Future
-Center for Data to HealthNoha Sharafeldin, MBBCh, MSc, PhD co-leads the Oncology Domain Team of the National COVID Cohort Collaborative (N3C). Dr. Sharafeldin will present the abstract titled: Outcomes of COVID-19 in Cancer Patients: Report From the National COVID Cohort Collaborative (N3C) at the American Society of Clinical Oncology (ASCO) annual meeting. The oral abstract is part of the Care Delivery and Regulatory-
May 06, 2021For the past year, researchers have been pursuing possibilities for the repurposing of existing drugs that can effectively disrupt COVID-19 disease processes. Electronic health record (EHR) data from the N3C Data Enclave were used to produce a recent preprint published in medRxiv on April 6, 2021 titled Drug repositioning candidates identified using in-silico quasi-quantum molecular simulation
-
Center for Data to Health
The attached files are provided to the CTSA Program Communications team for use in promoting and communication about the N3C.
The attached doc is guidance for how our hub partners should communicate about N3C efforts
-Center for Data to HealthFinding the right dataset can sometimes be a challenge in data science. A new initiative will provide Penn State researchers with access to a trove of COVID-19 data, updated frequently by health care systems around the United States. Penn State faculty can learn how to get access to the database and what data is included at a Data Science Community talk at 1 p.m. on Thursday, April 15. Advance-
April 07, 2021
Read the latest N3C preprint now published in medRxiv by authors: Joy Alamgir, Masanao Yajima, Rosa Ergas, Xinci Chen, Nicholas Hill, Naved Munir, Mohsan Saeed, Kenneth Gersing, Melissa Haendel, Christopher Chute, Ruhul Abid. Background: Drug repositioning is a key component of COVID-19 pandemic response, through identification of existing drugs that can effectively disrupt COVID-19 disease
March 05, 2021Melissa A. Haendel, PhD, has been named Chief Research Informatics Officer (CRIO) for the University of Colorado Anschutz Medical Campus, a newly created position responsible for transforming the campus use of information and information systems to accelerate biomedical discoveries, streamline health system operations, and continuously improve patient care. The CRIO office will lead efforts to
February 11, 2021NCATS has provided the FDA with access to the N3C Data Enclave. FDA investigators interested in accessing N3C COVID-19 data must complete appropriate human subjects and NIH security training, review and abide by NCATS technology transfer requirements, and submit a Data Use Request (DUR) detailing their proposed project and use of N3C data. For details on how FDA investigators can access the N3C
February 05, 2021Researchers have been anxious to learn what variables describe the COVID-19 patient cohort. Using the harmonized data in the N3C Data Enclave from 39 institutions’ electronic health records around the country, collaborators were able to distill this information in the manuscript titled The National COVID Cohort Collaborative: Clinical Characterization and Early Severity Prediction and is now-
February 04, 2021N3C held the first Enclave orientation sessions on February 2nd and 9th to engage users of all types with learning to use the N3C Data Enclave. The sessions were conducted by N3C Training Coordinator Shawn O’Neil and had over 100 participants for each session in attendance. This two-part training course will repeat on an ongoing basis, alternating week by week. To view training information and
-
-Center for Data to HealthN3C will hold a 2-part virtual orientation to learn how to use the N3C Data Enclave. These sessions are designed for users of all types. The first 2 sessions will take place in February, and then will alternate week by week for ongoing access. Session A - Recommended before attending Session B This session is for those who want to learn about N3C, as well as how to engage with project teams and
- January 20, 2021Organ transplant recipients, people with HIV, those with autoimmune diseases like rheumatoid arthritis and multiple sclerosis – the COVID-19 pandemic has been especially scary for people whose immune systems are compromised or suppressed. They’ve fought or are fighting battles against other diseases – or even their own immune systems. And the newness of the virus means no one is sure how they
-
January 15, 2021View the N3C abstract for the paper The National COVID Cohort Collaborative: Clinical Characterization and Early Severity Prediction published in medRxiv, the preprint server for health sciences. This abstract is a preprint and has not yet been certified by peer review, so should not be used to guide clinical practice at this time. Stay tuned for full article publication! doi: https://doi.org/10
To elicit participant feedback regarding the COVID-19 session during the Fall 2020 Program Meeting.
-
January 07, 2021
N3C is hosting an Open House to engage CTSA members, newcomers, and the wider translational research community. The event will be kicked off with a one-hour symposium that includes opening remarks from N3C leadership, followed by a PI/Clinician Testimonial with Dr. David Ellison of OCTRI, an N3C Tutorial on how to get involved, a demonstration of the N3C Data Enclave, and flash talks from the
-
-Center for Data to HealthN3C is hosting an Open House to engage CTSA members, newcomers, and the wider translational research community. The event will be kicked off with a one-hour Community Research Symposium, followed by a week of open community meetings to welcome new collaborators, present the work of the Domain Teams, and help researchers launch their COVID-19 projects. Kick-off Event: Community Research Symposium
-
December 04, 2020The National COVID Cohort Collaborative (N3C) is open for research with over 2 million patients and 2 billion rows of data from more than 35 sites. Nineteen multidisciplinary Domain Teams composed of clinical and subject matter experts, statisticians, informaticists, and machine learning specialists are addressing the most pressing clinical questions. N3C data can be utilized to understand COVID
-
Center for Data to Health
N3C Domain Teams enable researchers with shared interests to analyze data within the N3C Data Enclave and collaborate more efficiently in a team science environment.
-
-Center for Data to HealthFree webinar for HIMSS Innovation Community & HIMSS20 Artificial Intelligence & Machine Learning Circle COVID-19 raises many difficult questions: What are the key risk factors? What are the best prognostic indicators? Which drugs are the most viable candidates for patients? To address these questions and more, the National Center for Data to Health (CD2H) and National Center for Advancing
-
November 16, 2020Listen to the latest Bioinformatics & Beyond podcast hosted by Leo Elworth. Dr. Melissa Haendel discusses how the N3C organization she co-leads and co-founded has led the way in integrating COVID-19 clinical data to aid research efforts. She discusses how the creation of synthetic clinical data also has the potential to help COVID-19 researchers. Further topics include the current status of
-
November 13, 2020Anita Walden (CD2H/N3C), Nicole Garbarini (NCATS), Heidi Spratt (UTMB), Charisse Madlock-Brown (UTHSC), and Sally Hodder (WVU) give an overview and update on the status of the N3C and governance policy, with a focus on Clinical Domain Teams, IDeA-CTR partnership, and engagement. N3C overview and status updates Data agreements; status and process Domain Teams, value, and opportunities Social
November 13, 2020Data from more than 143,000 coronavirus-positive patients are now available to Rhode Island researchers through the new National COVID Cohort Collaborative (N3C) data platform. In addition to the vast amounts of data available for coronavirus research, the N3C also aims to help scientists analyze these data to understand the disease and develop treatments. The N3C Data Enclave was officially
November 10, 2020Regenstrief Institute, Indiana Clinical and Translational Sciences Institute (CTSI) and Datavant are supporting the National Institutes of Health (NIH) in a national effort to securely gather data to help scientists understand and develop treatments for COVID-19. The National COVID Cohort Collaborative (N3C) was launched as a centralized analytics platform to store and study vast amounts of-
November 06, 2020Built and launched in just a few short months, the National COVID Cohort Collaborative (N3C) was established with researchers from more than 300 institutions. Whether you’re a clinician, statistician, data scientist, or translational scientist of any kind, there are numerous ways to participate. The N3C Data Enclave opened on September 2nd and now has over 1 million patient records (over 1 billion
