University Of Utah
University of Utah
The CCTS is the home for clinical and translational science in our institutions, the state of Utah, and within the Mountain West Region. It builds on our strengths in genetics and bioinformatics to translate promising bench science into practices that improve human health.
The center serves as an academic home for clinical and translational research, developing innovative health services for the community and health researchers, and training a new generation of clinical and translational investigators. Four foundations of discovery compose the center: Clinical Trials Support, Population Health, Precision Medicine, and Workforce Development, and these foundations provide support for T1 to T4 research.
November 04, 2022The below article features Dr. Micah Drummond's research on muscle aging and rehabilitation. Dr. Drummond kindly shared how the CTSI helped him complete this important work: The research projects within Dr. Drummond’s laboratory hold to two general research themes: Understanding the cellular and molecular mechanisms of muscle growth and metabolic function in healthy and mobility impaired older
- Trial Innovation NetworkUniversity Of UtahVanderbilt University Medical CenterTufts University BostonJohns Hopkins UniversityDuke University
Daniel Benjamin, MD, PhD, MPH1; Gordon R. Bernard, MD2; J. Michael Dean, MD, MBA3; Daniel E. Ford, MD, MPH4; Daniel Hanley, MD4; Paul A. Harris, PhD, FACMI2; Harry Selker, MD, MSPH5; Consuelo H. Wilkins, MD, MSCI2 1Duke Clinical Research Institute, 2Vanderbilt Institute for Clinical and Translational Research, 3University of Utah, 4Johns Hopkins University, 5Tufts University ABSTRACT: The Trial
- University Of Utah
The use of Artificial Intelligence (AI) in medicine has attracted a great deal of attention in the medical literature, but less is known about how to assess the uncertainty of individual predictions in clinical applications. Here we demonstrate the use of Conformal Prediction (CP) to provide insight on racial stratification of uncertainty quantification for breast cancer risk prediction. We found
University Of UtahDr. Adam Ware discusses his research on pediatric cardiology and the impact CTSI has had on it.
-University Of UtahThe CTSA Visiting Scholar program consists of giving the virtual CTSA Grand Rounds lecture, which is open to the entire CTSA Consortium, and virtual meetings between KL2 Scholars and faculty at the host institution and their KL2 peers. There are two main goals of this program. The first is to offer the opportunity to serve as a visiting professor and help make connections with faculty that will
- University Of UtahUniversity Of Texas Health Science Center
A major impediment to dissemination and implementation of evidence-based medicine is mis- and disinformation, which are currently rampant. Mis- and disinformation influences health behaviors and results in adverse outcomes including delayed treatment, inappropriate self-treatment, low enrollment in clinical research, and health disparities. Raising awareness and increasing skills in addressing
- University Of UtahUniversity Of Texas Health Science Center
A major impediment to dissemination and implementation of evidence-based medicine is mis- and disinformation, which are currently rampant. Mis- and disinformation influences health behaviors and results in adverse outcomes including delayed treatment, inappropriate self-treatment, low enrollment in clinical research, and health disparities. Raising awareness and increasing skills in addressing
May 11, 2021Seemingly overnight, the entire world zeroed in on a single research topic. The World Health Organization had already declared COVID-19 a global health emergency, and in CTSA Program hubs across the United States, health and medical experts faced the same urgent challenge: the speed and efficiency of today’s technologically-driven global economy that enabled the Coronavirus to spread as quickly as-
May 03, 2021
Three outstanding faculty researchers have been named to hold prestigious H.A. and Edna Benning Presidential Endowed chairs in the University of Utah School of Medicine. The three new Benning Chairs are Rachel Hess, M.D., Louisa Stark, Ph.D., and Martin Tristani-Firouzi, M.D. Hess is chief of the Division of Health System Innovation and Research and co-principal investigator of the Utah Center for
University Of UtahNIH Heal Award winner and University of Utah researcher Julie Fritz discusses her expertise on musculoskeletal and back pain on the heels of winning being awarded the NIH HEAL Award grant.
University Of UtahResearch Assistant Professor of Internal Medicine Dr. Lindsay Keegan contributes her presentation "What Is Key Concepts in Infectious Disease Dynamics Through the Lens of COVID-19" to the TL1 "What Is?" Conference" series.
University Of UtahThe NCATS Life Course Research Visual Toolkit is an asynchronous population health science series broken down into broader themes within the discipline. Life course research embraces the complexity of health and disease development, tackling the extensive interactions between genetics and the environment. Recent advances in computational analytics, computer science, and data collection allow for
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University Of Utah
National Covid Cohort Collaborative (N3C) Co-Director and Professor of Medical Informatics and Clinical Epidemiology for Oregon Health and Science University comprehensively discusses N3C.
University Of UtahAssociate Professor of Population Health Sciences Dr. JD Smith presents "What Is Implementation Science?" as part of Utah CCTS' TL1 "What Is?" conference series.
April 19, 2021The Association for Clinical and Translational Science awarded Utah CTSI TL1 NIH Postdoctoral Fellow and NeuroRobotics Lab director Jacob George with this year's ACTS Postdoctoral Translational Science Award for his work at the intersection of robotics and neuroscience. Utah CTSI played an integral role in funding his studies as acknowledged in his tweet about the award. He explains his work in
Vasculitis refers to a group of rare diseases that involve inflammation of blood vessels, which disrupts blood flow and often causes damage to the body’s organs. The cause of most forms of vasculitis remains unknown, and treatments involve the use of strong medications that can have serious side effects. The Vasculitis Clinical Research Consortium (VCRC) is an international, multicenter clinical
The porphyrias are a group of rare, inherited disorders, each caused by a deficiency with one of eight enzymes necessary to produce heme, an important component of hemoglobin and other proteins. The porphyrias are classified as either acute hepatic (liver) or cutaneous (skin); the former is characterized generally by acute attacks of severe abdominal pain accompanied by nausea, vomiting and other
The Phenylalanine Families and Researchers Exploring Evidence (PHEFREE) Consortium studies the health, neurologic, cognitive, neuropsychiatric, patient-reported and quality-of-life outcomes in individuals with chronic elevations of the amino acid phenylalanine in blood (hyperphenylalaninemia). In the United States, elevated blood phenylalanine is typically detected at birth through newborn
Leukodystrophies are a complex, often progressive group of disorders affecting the white matter of the brain due to the loss or absence of myelin, the lipid membrane that insulates axons in the central nervous system. Despite advances in the diagnosis of these disorders, they remain widely under-recognized, with unmet gaps in clinical care and curative therapeutics. The Global Leukodystrophy
Eosinophilic esophagitis, eosinophilic gastritis, eosinophilic gastroenteritis, and eosinophilic colitis are disorders in which a type of immune cell (called eosinophils) builds up in the digestive tract, causing gastrointestinal tissue damage. These disorders are painful, lifelong, and make it hard or impossible for people to eat many or all foods. The Consortium of Eosinophilic Gastrointestinal
The Brain Vascular Malformation Consortium (BVMC) focuses on three rare brain conditions: familial cerebral cavernous malformation (CCM), Sturge-Weber syndrome (SWS), and hereditary hemorrhagic telangiectasia (HHT). These disorders are poorly understood, costly to manage, and can cause serious complications such as hemorrhages, seizures, and problems with spinal cord, nerve or brain function. Over
University Of UtahRacial/ethnic minority, low socioeconomic status (SES) and rural populations suffer profound health inequities across a wide variety of diseases and conditions, as well as a disproportionate burden of the negative health consequences of the COVID-19 pandemic. Latinos make up ~14% of the Utah population compared to ~28 of Utah’s COVID-19 cases, and the case rate is over 3-fold higher in
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University Of Utah
The What is? Seminar is a once-a-month 1-hour seminar on diverse translational topics across the continuum. The seminar series brings together program faculty, other experts across the University of Utah CCTS, and visiting scholars who will present an educational perspective of their research/expertise area. This course provides training on diverse translational topics across the continuum. For
May 21, 2020A New Focus Even though we as a group are introverted scientists, I think we are learning how much of our routine is predicated on social interaction. We are always talking with colleagues and walking over to the next lab for a piece of advice or to borrow some trivial reagent. It’s so important to be able to think out loud or ask a colleague about some detail. This is all much more difficult
The Greater Plains Collaborative (GPC) is a network of 12 leading medical centers in eight states committed to a shared vision of improving healthcare delivery through ongoing learning, adoption of evidence-based practices, and active research dissemination. GPC builds on strong research programs at individual sites, existing community engagement and informatics infrastructures and data warehouses
The Consortium of Rural States (CORES) was formed to facilitate collaborative and disciplined efforts that will produce new opportunities for advancing translational research. The Collaborative comprises Arkansas, Kansas, New Mexico and Utah, states that share common health care challenges, including significant rural populations. Each state is served by a single Clinical and Translational
-University Of UtahThe Utah CCTS is hosting their second annual Research Trainee Symposium on November 7, 2019. This all-day symposium, which will be held at the Alumni House on the Campus of the University of Utah, will include oral and poster presentations by trainees, as well as a keynote address from an invited guest with a distinguished career in mentorship. The day will end in a celebratory dinner.
University Of UtahThe Utah CCTS Cellular Translational Research Core (CTRC) was officially launched in 2016 as a part of the Utah CCTS Precision Medicine program. The main CTRC priorities have been 1) to provide support and services for the investigators interested in stem cell research; 2) establish new services related to the generation of CRISPR/Cas9-edited human stem cell lines; and 3) educate the community on